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Horse chestnut ( Aesculus hippocastanum ) Tincture - 50 ml

R 10600
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Description

Horse chestnut ( Aesculus hippocastanum ) Tincture - 50 ml


     

    TRADITIONALLY USED FOR

     May help with

     

    • Venous circulatory tonic - varicose veins
    • hemorrhoids
    • anti-inflammatory

    INFORMATION

    Source : http://www.wikiphyto.org/wiki/Horse chestnut

     

    Reference on http://www.wikiphyto.org

     

    Translation in English by Google Translate  (go to the page of the source linked | on Chrome cellphones go on the 3 dots on the top right and select translate in your preferred language | on laptop right click your mouse and select option translate when hoovering on the page

     

    plant name

     

    Horse Chestnut, Horse Chestnut , Horse Chestnut

     

    International Latin denomination

     

    Aesculus hippocastanum L.

     

    botanical family

     

    Hippocastanaceae

     

    Description and habitat

     

    • Superb ornamental tree
    • Native to Asia Minor and Northern Greece (but not India)
    • Introduced in Europe in the 17th century
    • Palmately compound leaves, long petiolate
    • Fragrant flowers, grouped in clusters of pyramid-shaped cymes, white petals spotted with pink
    • The fruit is a spiny capsule

     

    History and tradition

     

    • The flour was added to the oats to feed the winded horses (hence its vernacular name of Chestnut horse )

     

    Parts used

     

    • Seeds

     

    Dosage forms available

     

    • Seed tincture with integument
    • Fluid extract
    • Dry extract
    • EPS
    • Intrait :
      • Composition of the drug HORSE CHESTNUT INTRACT p 100 drops (Vidal [3] )
      • The intract is a stabilized dry extract titrated to 2% esculoside . Stabilization consists of stopping enzymatic degradation by hot water vapor just after picking, to maintain the content of active ingredients. Then we make a dry extract which will be dissolved in a hydro-alcoholic solvent to obtain the liquid product called intrait itself.

     

    Usual dosages

     

    Composition

     

    Main components of the plant

     

     

    Main components of buds or young shoots

     

     

    Main components of essential oil

     

    Properties

     

    Plant properties

     

    • Anti-inflammatory, anti-edematous, anti-exudative (on “inflammatory models”) [6]
    • Increase in venous tone, venous vasoconstrictor [7] , [8] , venotonic by inhibition of hyaluronidase which degrades hyaluronic acid, glycosaminoglycan of connective tissues [9]
    • Reduction of capillary permeability and reinforcement of capillary resistance
    • Anti-radical and antioxidant [10]
    • Decreased ethanol absorption and hypoglycemic effect ( escins ) [11] , [12]
    • Stimulation des enzymes lysosomiales
    • Increased ACTH and corticosteroids
    • The bark of young stems is astringent and febrifuge

     

    Bud properties

     

    • Venous circulatory tonic

     

    Properties of essential oil

     

    Indications

     

    Indications of the whole plant (phytotherapy)

     

    • Venous and lymphatic insufficiency [13] , [14] , [15] , varicose veins, phlebitis, hemorrhoids and hemorrhoidal crisis
    • Prostate enlargement, pelvic congestion
    • Dysmenorrhea of ​​circulatory origin
    • Canker sores, ulcerations of the oral mucosa
    • Capillary fragility disorders (association with flavonoids , butcher's broom extract , local anesthetics, tocopherol, etc.)

     

    Indications of the bud (gemmotherapy)

     

    • Varicose veins, hemorrhoids, varicose ulcers
    • Troubles prostatiques

     

    Specific indications of essential oil (aromatherapy)

     

    Known or suspected mode of action

     

    • Action of escin on lysosomal enzymes

     

    Usual formulations

     

    Regulations

     

     

    Possible side effects and precautions for use

     

    • Avoid during pregnancy and lactation, in case of diabetes, latex allergy, do not use before surgery (hemorrhagic risk)
    • Possibility of interaction with plants and anticoagulant [16] and hypoglycemic drugs
    • Nephrotoxicity at high doses therefore contraindication in renal failure

     

    Bibliographic references

     

    1. Go↑ Yoshikawa M, Murakami T, Matsuda H, Yamahara J, Murakami N, Kitagawa I. Bioactive saponins and glycosides. III. Horse chestnut. (1): The structures, inhibitory effects on ethanol absorption, and hypoglycemic activity of escins Ia, Ib, IIa, IIb, and IIIa from the seeds of Aesculus hippocastanum L. Chem Pharm Bull (Tokyo). 1996 Aug;44(8):1454-64. PMID 8795266
    2. Go↑ Becker LC, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Alan Andersen F. Final report of the safety assessment of allantoin and its related complexes. Int J Toxicol. 2010 May;29(3 Suppl):84S-97S. doi: 10.1177/1091581810362805. PMID 20448269
    3. Go↑ Egger K, Wollenweber E, Tissut M. Free flavonol aglycones in the secretion of the buds of Aesculus spp. Zeitschrift fur Pflanzenphysiologie 1970 Vol. 62 No. 5 pp. 464-6 [1]
    4. Go↑ Feucht W, Treutter D. Flavan-3-ols in Trichomes, Pistils and Phelloderm of Some Tree Species. Ann Bot (1990) 65(2): 225-230
    5. Go↑ J. Deli, Z. Matus, G. Tóth. Comparative study on the carotenoid composition in the buds and flowers of different Aesculus species. Chromatographia, Volume 51, Number 1 (2000), S179-S182 [2]
    6. Go↑ Matsuda H, Li Y, Murakami T, Ninomiya K, Yamahara J, Yoshikawa M. Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. Biol Pharm Bull. 1997 Oct;20(10):1092-5. PMID 9353571
    7. Go↑ Pittler MH, Ernst E. Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review. Arch Dermatol. 1998 Nov;134(11):1356-60. PMID 9828868
    8. Go↑ Suter A, Bommer S, Rechner J. Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies. Adv Ther. 2006 Jan-Feb;23(1):179-90. PMID 16644618
    9. Go↑ Facino RM, Carini M, Stefani R, Aldini G, Saibene L. Anti-elastase and anti-hyaluronidase activities of saponins and sapogenins from Hedera helix, Aesculus hippocastanum, and Ruscus aculeatus: factors contributing to their efficacy in the treatment of venous insufficiency. Arch Pharm (Weinheim). 1995 Oct;328(10):720-4. PMID 8554461
    10. Go↑ Masaki H, Sakaki S, Atsumi T, Sakurai H. Active-oxygen scavenging activity of plant extracts. Biol Pharm Bull. 1995 Jan;18(1):162-6. PMID 7735233
    11. Go↑ Yoshikawa M, Harada E, Murakami T, Matsuda H, Wariishi N, Yamahara J, Murakami N, Kitagawa I. Escins-Ia, Ib, IIa, IIb, and IIIa, bioactive triterpene oligoglycosides from the seeds of Aesculus hippocastanum L.: their inhibitory effects on ethanol absorption and hypoglycemic activity on glucose tolerance test. Chem Pharm Bull (Tokyo). 1994 Jun;42(6):1357-9. PMID 8069982
    12. Go↑ Yoshikawa M, Murakami T, Matsuda H, Yamahara J, Murakami N, Kitagawa I. Bioactive saponins and glycosides. III. Horse chestnut. (1): The structures, inhibitory effects on ethanol absorption, and hypoglycemic activity of escins Ia, Ib, IIa, IIb, and IIIa from the seeds of Aesculus hippocastanum L. Chem Pharm Bull (Tokyo). 1996 Aug;44(8):1454-64. PMID 8795266
    13. Go↑ Suter A, Bommer S, Rechner J. Treatment of patients with venous insufficiency with fresh plant horse chestnut seed extract: a review of 5 clinical studies. Adv Ther. 2006 Jan-Feb;23(1):179-90. PMID 16644618
    14. Go↑ Siebert U, Brach M, Sroczynski G, Berla K. Efficacy, routine effectiveness, and safety of horsechestnut seed extract in the treatment of chronic venous insufficiency. A meta-analysis of randomized controlled trials and large observational studies. Int Angiol. 2002 Dec;21(4):305-15. PMID 12518108
    15. Go↑ Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev. 2012 Nov 14;11:CD003230. doi: 10.1002/14651858.CD003230.pub4. PMID 23152216
    16. Go↑ Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. American Journal of Health-System Pharmacy July 1, 2000 vol. 57 no. 13 1221-1227
    • Bruneton Jean. Pharmacognosy, Phytochemistry, Medicinal Plants. Ed. Tec and Doc. 1997 p. 555
    • Cecile Vieu. The horse chestnut (Aesculus hippocastanum L.): botanical, chemical and therapeutic studies. Pharmaceutical sciences. 2014.dumas-01006873

    CAUTION

    Store in a cool, dry place, away from light. Keep tightly closed, away from the reach of Children and pets.

    Do not exceed the daily dose.

     

    This product is not intended to prevent or cure any form of illness or disease.
     

    If you are pregnant or nursing ; If you have a medical condition or are in the course of medical treatment ; If you are programmed for theater/operation in the near future, please consult your healthcare practitioner before using this product.

     

    This product cannot replace a varied and balanced diet and a healthy lifestyle.

     

    This product has not been evaluated by the SAHPRA for its quality, safety or intended use.

     

    For More Information please check our General Safety Herbal products Page