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Goats Rue Herb Cut - 75 g - Herbal Collection

R 5900
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Description

Goats Rue Herb Cut - 75 g - Herbal Collection

Galega officinalis


    TRADITIONALLY USED FOR

    May help with

     

    • Diuretic
    • weight loss
    • lactation - milk secretion - breastfeeding
    • anti diabetic - obesity

     

     

     

    INFORMATION

    Source : http://www.wikiphyto.org/wiki/Galega

     

    Reference on http://www.wikiphyto.org

     

    Translation in English by Google Translate  (go to the page of the source linked | on Chrome cellphones go on the 3 dots on the top right and select translate in your preferred language | on laptop right click your mouse and select option translate when hoovering on the page

     

    plant name

     

    Galega, galega galega , goat 's rue , Spanish sainfoin , false indigo , goat's rue , french lilac or Italian fitch (English), Geissrautenkraut (German)

     

    International Latin denomination

     

    Galega officinalis L.

     

    botanical family

     

    Fabaceae subfamily Faboideae (ex - Papilionaceae , ex - Leguminosae )

     

    Description and habitat

     

    • Perennial bush with compound leaves, lanceolate leaflets, delicate pink flowers resembling those of the pea and arranged on terminal spikes, with brown-red pods in autumn (1 m high)
    • Rather Mediterranean, native to Asia and Western Europe, humid plains

     

    History and tradition

     

    • Formerly used to cure the plague
    • Professor Jean Sterne (1909–1997) of Laennec Hospital in Paris was the first to work on galegine , which led to the discovery of biguanides and metformin
    • The aerial parts of the plant are toxic during flowering and fruiting in animals (4 kg of fresh plant for a cow, 400 g for a sheep)

     

    Parts used

     

     

    Dosage forms available

     

     

    Usual dosages

     

    • Infusion of 2 grams of drug

     

    Composition

     

    Main components of the plant

     

     

    Main components of buds or young shoots

     

    Main components of essential oil

     

    Properties

     

    Plant properties

     

    • Antidiabetic properties [1] , inhibits glucose transport through the intestinal wall [2]
    • Galegin , considered a glucokinin, greatly lowers blood sugar levels. It can be effective in the early stages of diabetes, especially in the form of an infusion
    • Metformin (biguanide), a first-line drug in the treatment of type 2 diabetes, is derived from galega [3] , [4]
    • Promotes weight loss ( dimethylallylguanidine = galegin ) [5] , [6] , [7] , [8]
    • Inhibits platelet aggregation ( polysaccharides ) [9] , [10] , [11]
    • Diuretic
    • Promotes lactation in breastfeeding women, traditional use without scientific studies [12] , [13] , [14]
    • Moderate antibacterial activity [15]
    • Danger of poisoning from high-dose guanidines
    • An aqueous extract at 12.5 g/kg of body weight lowers blood sugar by 66% compared to the control, in one hour

     

    Bud properties

     

    Properties of essential oil

     

    Directions

     

    Indications of the whole plant (phytotherapy)

     

    • Can be used in early forms of diabetes with obesity [16]
    • Milky insufficiency (?) poorly documented [2] , recommended therapeutic dose in tincture: 1 to 2 ml, 3 times a day.
    • Obesity and Metabolic Syndrome

     

    Indications of the bud (gemmotherapy)

     

    Specific indications of essential oil (aromatherapy)

     

    Known or suspected mode of action

     

    • Likely inhibition of hepatic glucose production by galegin (like metformin)
    • Lectins bind to sugar receptors on cell membranes

     

    Usual formulations

     

    Regulations

     

     

    Possible side effects and precautions for use

     

    • Not recommended in established diabetes, due to its uncertain effect and the severity of the declared disease
    • Possible interactions with biguanides (metformin)
    • Toxic to sheep (about 500 grams causes lung edema and convulsions) [17]
    • Human toxicity is poorly evaluated but seems low
    • The seed is poisonous

     

    Bibliographic references

     

    1. Aller↑ Pundarikakshudu K, Gray AI, Furman BL. Studies on the hypoglycaemic activity of Galega officinalis (goat's rue). Fitoterapia, 1994, vol. 65, no.5, pp. 423-426
    2. Aller↑ Neef H, Augustijns P, Declercq P, Laekeman G. Inhibitory effects of Galega officinalis on glucose transport across monolayers of human intestinal epithelial cells (Caco-2). Pharmaceutical and Pharmacological Letters 1996, vol:6 issue:2 pages:86-89
    3. Aller↑ Hadden DR. Goat's rue - French lilac - Italian fitch - Spanish sainfoin: gallega officinalis and metformin: the Edinburgh connection. JR Coll Physicians Edinb. 2005 Oct;35(3):258-60. PMID 16402501
    4. Aller↑ Bailey CJ, Day C. Metformin: its botanical background. Practical Diabetes International, Volume 21, Issue 3, pages 115–117, April 2004 full text
    5. Aller↑ Coxon GD, Furman BL, Harvey AL, McTavish J, Mooney MH, Arastoo M, Kennedy AR, Tettey JM, Waigh RD. Benzylguanidines and other galegine analogues inducing weight loss in mice. J Med Chem. 2009 Jun 11;52(11):3457-63. PMID 19422230
    6. Aller↑ Palit P, Furman BL, Gray AI. Novel weight-reducing activity of Galega officinalis in mice. J Pharm Pharmacol. 1999 Nov;51(11):1313-9. PMID 10632090
    7. Aller↑ Mooney MH, Fogarty S, Stevenson C, Gallagher AM, Palit P, Hawley SA, Hardie DG, Coxon GD, Waigh RD, Tate RJ, Harvey AL, Furman BL. Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice. Br J Pharmacol. 2008 Apr;153(8):1669-77. PMID 18297106
    8. Aller↑ Palit P, Furman BL, Gray AI. Novel weight-reducing activity of Galega officinalis in mice. J Pharm Pharmacol. 1999 Nov;51(11):1313-9. PMID 10632090
    9. Aller↑ Atanasov AT, Tchorbanov B. Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation. J Med Food. 2002 Winter;5(4):229-34. PMID 12639398
    10. Aller↑ Atanasov AT, Spasov V. Inhibiting effect of desalted extract from Galega officinalis L. on platelet aggregation. Folia Med (Plovdiv). 1999;41(1):46-50. PMID 10462920
    11. Aller↑ Atanasov AT, Spasov V. Inhibiting and disaggregating effect of gel-filtered Galega officinalis L. herbal extract on platelet aggregation. J Ethnopharmacol. 2000 Mar;69(3):235-40. PMID 10722205
    12. Aller↑ Zuppa AA, Sindico P, Orchi C, Carducci C, Cardiello V, Romagnoli C. Safety and efficacy of galactogogues: substances that induce, maintain and increase breast milk production. J Pharm Pharm Sci. 2010;13(2):162-74. PMID 20816003 Full Text
    13. Aller↑ Leche league
    14. Aller↑ ABM Clinical Protocol #9: Use of Galactogogues in Initiating or Augmenting the Rate of Maternal Milk Secretion (First Revision January 2011). BREASTFEEDING MEDICINE Volume 6, Number 1, 2011. Mary Ann Liebert, Inc. [1]
    15. Aller↑ Pundarikakshudu K, Patel JK, Bodar MS, Deans SG. Anti-bacterial activity of Galega officinalis L. (Goat's Rue). J Ethnopharmacol. 2001 Sep;77(1):111-2. PMID 11483386
    16. Aller↑ Vuksan V, Sievenpiper JL. Herbal remedies in the management of diabetes: lessons learned from the study of ginseng. Nutr Metab Cardiovascular Dis. 2005 Jun;15(3):149-60. PMID 15955462
    17. Aller↑ Puyt JD, Faliu L, Keck G, Gedfrain JC, Pinault L, Tainturier D. Fatal poisoning of sheep by Galega officinalis (French honeysuckle). Vet Hum Toxicol. 1981 Dec;23(6):410-2. PMID 7336561 .
    • Goetz P, Le Jeune R. Galega officinalis. Materia Medica. Phytotherapy, Volume 6, Number 1 / February 2008. [3]
    • Witters Lee A. The blooming of the French lilac (Galega officinalis). J Clin Invest. 2001 October 15; 108(8): 1105–1107. [4]
    • Rasekh HR, Nazari P, Kamli-Nejad M, Hosseinzadeh L. Acute and subchronic oral toxicity of Galega officinalis in rats. Journal of ethnopharmacology 2008, vol. 116, no.1, pp. 21-26 [5]
    • Heiss H. Clinical and experimental contribution on the question of the lactogenic effect of Galega officinalis. Vienna Med Wochenschr. 1968 Jun 15;118(24):546-8. PMID 5751861
    • Barthel A, Reuter G. Biochemistry and physiology of isoprenoid guanidines, especially (4-hydroxy-3-methyl-2-buten-1-yl)guanidine in Galega officinalis. Pharmacy. 1968;23:26-33
    • Hui H, Tang G, Go VL. Hypoglycemic herbs and their action mechanisms. Chin Med. 2009 Jun 12;4:11. PMID 19523223 Full text: [6]
    • Drug Information Online: Complete Goat's Street information from Drugs.com [7]

    CAUTION

    Store in a cool, dry place, away from light. Keep tightly closed, away from the reach of Children and pets.

    Do not exceed the daily dose.

     

    This product is not intended to prevent or cure any form of illness or disease.
     

    If you are pregnant or nursing ; If you have a medical condition or are in the course of medical treatment ; If you are programmed for theater/operation in the near future, please consult your healthcare practitioner before using this product.

     

    This product cannot replace a varied and balanced diet and a healthy lifestyle.

     

    This product has not been evaluated by the SAHPRA for its quality, safety or intended use.

     

    For More Information please check our General Safety Herbal products Page