Rosemary Herbal Extract ( Rosemarianus officinalis ) - 50 ml
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Rosemary Herbal Extract ( Rosemarianus officinalis ) - 50 ml
May help with
- Cardiac tonic
- expectorant - Pulmonary antiseptic
- Memory enhancement
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Rosemary , Crown Grass
International Latin denomination
Description and habitat
- Evergreen bushy shrub, with sessile, linear and leathery dark green leaves, with a characteristic aromatic odor (camphorous, imitating the smell of incense )
- Inflorescences of pale blue or light lilac flowers smeared with purple spots
- Very polymorphic, there are several chemotypes depending on the geographical origin:
History and tradition
- Introduced in the medicinal plant gardens of the Middle Ages
- Emblem of triumph among the Greeks and Romans
- Rosemary is one of the great preventive and protective plants (like many plants of the Labiatae family )
- Vulnerable species or "Swiss tea" from the 1949 Codex: leaves and tops of wormwood , betony , calament , germander , hyssop , ground ivy , oregano , periwinkle , rosemary , sage , scolopendra , scordium , thyme , veronica ; arnica flowers , cat's foot , coltsfoot ; in equal parts
- flowering top
- Flowering tops essential oil
Dosage forms available
Main components of the plant
- Essential oil (1 to 2.5%)
- Methylated flavones : genkwanin , luteolin , diosmetin , apigenin , isoscutellarein -7-O-glucoside
- Phenol acids : rosmarinic acid also called " Labiae tannin "
- Tricyclic phenolic diterpenes: rosmaridiphenol , carnosolic acid (= carnosic acid ), rosmadial , ( carnosol = picrosalvin , rosmanol )
- Acidic polysaccharides (6%)
- Triterpenes and steroids : oleanolic acid , derivatives of ursolic acid
Main components of buds or young shoots
- Monoterpene hydrocarbons , borneol , bornyl acetate , terpineol , terpinene-4-ol more abundant in young leaves than in adult leaves, few camphor and verbenone the amounts of which increase steadily with leaf growth  , rosmarinic acid , of higher concentration, on the other hand, in the aqueous extracts of young shoots 
Main components of essential oil
- Three chemotypes :
- 1) Camphor chemotype ( 30%), 1,8-cineole (15-30%), alpha-pinene (25%), free and esterified borneol (1-5%), alpha-terpineol (12-24%) , limonene , camphene , beta-pinene , beta-caryophyllene , myrcene , etc.
- 2) Chemotype with 1,8-cineole 45%, camphor 8%, alpha-pinene (10%), beta-pinene 8%, beta-caryophyllene (3%)
- 3) Chemotype with verbenone and bornyl acetate , alpha-pinene , 1,8-cineole , camphor
- Choleretic and cholagogue, carminative, stimulation of digestive secretions, anti-ulcer (hydro-alcoholic extracts 
- Protection of the hepatocyte against peroxidation and toxins by aqueous and hydro-alcoholic extracts, diterpenes: rosmanol and carnosol  ,  , 
- Experimentation with rosemary extract on cultured hepatocytes demonstrated a protective action against the peroxidative effects of tert-butyl hydroperoxide.
- The effect of the young shoot is greater than that of the adult leaf 
- Nephroprotective 
- Demonstrated pharmacological actions: relaxation of bronchial and intestinal smooth muscles, anti-inflammatory effect by reduction of leukotrienes and increase in the production of PGE2, inhibition of complement and lipid peroxidation, prevention of carcinogenicity linked to the formation of adducts of DNA 
- Carnosol protects brain dopaminergic black cells (5) and carnosic acid increases the synthesis of nerve growth factor NGF 
- Carnosol protects dopaminergic neurons [ 11]
- Diuretic, tonic and stimulant
- Cardiac tonic ( oleanolic acid , ursolic acid ), inhibition of lipid peroxidation 
- Analgesic, like many plants of the Lamiaceae family 
- Spasmolytic by its essential oil
- Anti-inflammatory 
- Anticonvulsant (must depend on dose)
- Inhalation causes hyperactivity
- Antiviral  (le carnosol est antiviral)
- Increase in the antibacterial activity of antibiotics and decrease in resistance  , in vitro anti - Helicobacter pylori activity 
- Anti-acne potentialities (decreases inflammation induced by Propionibacterium acnes ) 
- Antioxidant activity  ( carnosol , carnosic acid ), interesting in cancers (prostate) 
- The powerful antioxidant activity has caught the attention of food manufacturers; partly linked to rosmarinic acid , it is mainly due to diterpenic 0-diphenols ( carnosic acid ) whose effectiveness has been evaluated on different models and deemed sufficient (≥ to that of BHT) for extracts to be marketed (France , USA, Germany)
- Rosemary extracts are primary antioxidants, acting as proton donors during the formation of free radicals. They significantly delay fat oxidation in lipid and food systems
- Protein glycation inhibitor 
- Anti-proliferative effect 
- The main constituents of Rosmarinus officinalis extract are camphor essential oil ( 15-25%), 1,8-cineole (15-30%), alpha-pinene (25%) and borneol , free and esterified, phenolic compounds represented by a dozen flavonoids with methylated genins and by phenolic acids , in particular rosmarinic acid .
- Hepatoprotective, according to Fleurentin, young rosemary shoots are more active in hepatic protection than adult plant preparations 
- Cholagogue and choleretic, diuretic 
- For Pol Henry hepatodigestive allergy 
Properties of essential oil
- Anti-inflammatory by inhibition of leukocyte migration  and analgesic 
- Antimicrobial 
- Antibacterial, antifungal, decreases the resistance of Escherichia coli to antibiotics and of Candida albicans to antifungals 
- Agonist effect on alpha-1 and alpha-2 adrenergic receptors, which leads to a decrease in the secretion and effects of catecholamines on the vessels 
- The essential oil of Rosmarinus officinalis , ct cineole applied topically has a vasodilating and warming effect which helps to improve Raynaud's phenomenon  , increases the perception of heat in patients with Raynaud's phenomenon linked to systemic sclerosis, without increasing the skin temperature measured by infrared thermography 
- Antioxidant and DNA protector 
- Neurotoxic ( camphor ) but hepatoprotective at low doses  ,  if camphor is not higher than 10-15%
- Expectorant, pulmonary antiseptic ( mainly 1,8-cineole chemotype )
- Inhalation of HE ( 1,8-cineole chemotype ) improves memory capacities  , 
- More specific indications of the different chemotypes :
Indications of the whole plant (phytotherapy)
- Digestive and hepatobiliary disorders
- Asthenia, convalescence
- Infectious diseases and their consequences
- External use in rheumatism
- small heart failures
- The effect of the young shoot is superior to that of the adult leaf in hepatoprotection
Indications of the bud (gemmotherapy)
Specific indications of essential oil (aromatherapy)
- Asthenia, overwork
- External use :
Known or suspected mode of action
- Rosmarinic acid is anti-asthenic and antiviral
- Carnosol and carnosic acid are powerful antioxidants (like rosmarinic acid ) in food
- Oleanolic acid and ursolic acid are heart tonic
- Camphor is a pulmonary antiseptic and cardio-respiratory stimulant, relaxing smooth and striated muscles, externally revulsive, and slightly anesthetic
- French Pharmacopoeia list A (leaf, flowering top)
Possible side effects and precautions for use
- Plant: bile duct obstruction, gallstones EMA, Assessment report on Rosmarinus officinalis L., aetheroleum and Rosmarinus officinalis L., folium
- Camphor essential oil is neurotoxic and its oral use should be avoided, epileptising, can cause nephritis and gastroenteritis
- The other two chemotypes are more reassuring, the LD50 of the HE of rosemary with verbenone would be 7220 mg/kg and that of rosemary with 1,8-cineole of 8080 mg/kg .
- Avoid rosemary during pregnancy
- Go↑ K.E. Rasmussen, S. Rasmussen, A. Baerheim svendsen. Quantitative determination of the various compounds of the volatile oil in small amouts of plant material by means of gas liquid chromatography. Terpenes and related compounds. Pharm Weekblad, 107, pp.277-284, 1972.
- Go↑ Hoefler C. Contribution to the pharmacological study of extracts of Rosmarinus officinalis L., and in particular of young shoots: choleretic, anti-hepatotoxic, anti-inflammatory and diuretic activities, University of Metz, Center for Environmental Sciences: thesis doctorate, specialty pharmacognosy, 1994.
- Go↑ Dias PC, Sheet MA, Potenti A, de Carvalho JE. Antiulcerogenic activity of crude hydroalcoholic extract of Rosmarinus officinalis L. J Ethnopharmacol. 2000 Jan; 69 (1): 57-62
- Go↑ Joyeux M, Rolland A, Fleurentin J, Mortier F, Dorfman P. tert-Butyl hydroperoxide-induced injury in isolated rat hepatocytes: a model for studying anti-hepatotoxic crude drugs. Planta Med. 1990 Apr;56(2):171-4. PMID 2353064
- Go↑ Sotelo-Felix JI, Martinez-Fong D, Muriel De la Torre P. Protective effect of carnosol on CCl(4)-induced acute liver damage in rats. Eur J Gastroenterol Hepatol. 2002 Sep;14(9):1001-6. PMID 12352220
- Go↑ Sotelo-Felix JI, Martinez-Fong D, Muriel P, Santillan RL, Castillo D, Yahuaca P. Evaluation of the effectiveness of Rosmarinus officinalis (Lamiaceae) in the alleviation of carbon tetrachloride-induced acute hepatotoxicity in the rat. J Ethnopharmacol. 2002 Jul;81(2):145-54. PMID 12065145
- Go↑ Fleurentin Jacques. Plants that heal us. Ed. West France. 2007
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- Go↑ Kosaka K, Yokoi T. Carnosic acid, a component of rosemary (Rosmarinus officinalis L.), promotes synthesis of nerve growth factor in T98G human glioblastoma cells. Biol Pharm Bull. 2003 Nov;26(11):1620-2
- Go↑ Kim SJ, Kim JS, Cho HS, Lee HJ, Kim SY, Kim S, Lee SY, Chun HS. Carnosol, a component of rosemary (Rosmarinus officinalis L.) protects nigral dopaminergic neuronal cells. Neuroreport. 2006 Nov 6;17(16):1729-33. PMID 17047462
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- Go↑ Uritu, C.M., Mihai, C.T., Stanciu, G., Dodi, G., Alexa-Stratulat, T., Luca, A., Leon-Constantin, M., Stefanescu, R., Bild, V., Melnic, S., & Tamba, B.I. (2018). Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review. Pain research & management. DOI:10.1155/2018/7801543 texte intégral
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- Go↑ del Bano MJ, Lorente J, Castillo J, Benavente-Garcia O, del Rio JA, Ortuno A, Quirin KW, Gerard D. Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Antioxidant activity. J Agric Food Chem. 2003 Jul 16;51(15):4247-53 PMID 12848492
- Go↑ Nolkemper S, Reichling J, Stintzing FC, Carle R, Schnitzler P. Antiviral effect of aqueous extracts from species of the Lamiaceae family against Herpes simplex virus type 1 and type 2 in vitro. Planta Med. 2006 Dec;72(15):1378-82. PMID 17091431
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- Go↑ Mahady GB, Pendland SL, Stoia A, Hamill FA, Fabricant D, Dietz BM, Chadwick LR. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother Res. 2005 Nov;19(11):988-91. PMID 16317658
- Go↑ Tsai TH, Chuang LT, Lien TJ, Liing YR, Chen WY, Tsai PJ. Rosmarinus officinalis extract suppresses Propionibacterium acnes-induced inflammatory responses. J Med Food. 2013 Apr;16(4):324-33. doi: 10.1089/jmf.2012.2577. PMID 23514231
- Go↑ Schwarz K, Ternes W. Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. II. Isolation of carnosic acid and formation of other phenolic diterpenes. Z Lebensm Unters Forsch. 1992 Aug;195(2):99-103. PMID 1529648
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- Go↑ Kim HY, Kim K. Protein glycation inhibitory and antioxidative activities of some plant extracts in vitro. J Agric Food Chem. 2003 Mar 12;51(6):1586-91. PMID 12617589
- Go↑ Cheung S, Tai J. Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis. Oncol Rep. 2007 Jun;17(6):1525-31. PMID 17487414
- Go↑ Hoefler C, Fleurentin J, Mortier F, Pelt JM, Guillemain J. "Comparative choleretic and hepatoprotective properties of young sprouts and total plant extracts of Rosmarinus officinalis in rats". J Ethnopharmacol. 1987 Mar-Apr;19(2):133-43. 
- Go↑ Viriot Anne-Claire. An update on gemmotherapy in 2012. Pharmacy thesis, Toulouse, 2015
- Go↑ Henry Pol. Gemmotherapy, therapy with plant embryonic extracts. Author's edition. Brussels, 1982.
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- Go↑ Takaki I, Bersani-Amado LE, Vendruscolo A, Sartoretto SM, Diniz SP, Bersani-Amado CA, Cuman RK. Anti-inflammatory and antinociceptive effects of Rosmarinus officinalis L. essential oil in experimental animal models. J Med Food. 2008 Dec;11(4):741-6. PMID 19053868
- Go↑ Jirovetz L, Buchbauer G, Denkova Z et all. Antimicrobial testings and gas chromatographic analysis of pure oxygenated monoterpenes 1,8-cineol, alpha-terpineol, terpinene-4-ol and camphor as well as target compounds in essential oils of pine (Pinus pinaster), rosemary (Rosmarinus officinalis), and tea-tree (Melaleuca alternifolia). Sci Pharm.2005. 73: 27-39. 
- Go↑ Luqman S, Dwivedi GR, Darokar MP, Kalra A, Khanuja SP. Potential of rosemary oil to be used in drug-resistant infections. Altern Ther Health Med. 2007 Sep-Oct;13(5):54-9. PMID 17900043
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- Go↑ Vagedes J, Henes J, Deckers B, Vagedes K, Kuderer S, Helmert E, von Schoen-Angerer T. Topical Rosmarinus officinalis L. in Systemic Sclerosis-Related Raynaud's Phenomenon: An Open-Label Pilot Study. Complement Med Res. 2022 Feb 9. doi: 10.1159/000522507. PMID 35139518.
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- Catherine Ulbricht , PharmD, Tracee Rae Abrams , PharmD, Ashley Brigham , PharmD, James Ceurvels , PharmD, Jessica Clubb , PharmD, Whitney Curtiss , PharmD, Catherine DeFranco Kirkwood , MPH, CCCJS-MAC, Nicole Giese , MS, Kevin Hoehn , PharmD, MBA, CGP, Ramon Iovin , PhD, Richard Isaac, Erica Rusie , PharmD, Jill M. Grimes Serrano , PhD, Minney Varghese, Wendy Weissner , BA & Regina C. Windsor , MPH. An Evidence-Based Systematic Review of Rosemary (Rosmarinus officinalis). Natural Standard Research Collaboration, Pages 351-413 
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Store in a cool, dry place, away from light. Keep tightly closed, away from the reach of Children and pets.
Do not exceed the daily dose.
This product is not intended to prevent or cure any form of illness or disease.
If you are pregnant or nursing ; If you have a medical condition or are in the course of medical treatment ; If you are programmed for theater/operation in the near future, please consult your healthcare practitioner before using this product.
This product cannot replace a varied and balanced diet and a healthy lifestyle.
This product has not been evaluated by the SAHPRA for its quality, safety or intended use.