May help with 

• Prostate problems

Source : http://www.wikiphyto.org/wiki/Willow herb

Reference on http://www.wikiphyto.org

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plant name

Fireweed, Fireweed

International Latin denomination

Chamaenerion angustifolium (L.) Scop., Epilobium angustifolium L.

botanical family

Oenotheraceae (Onagraceae)

Description and habitat

Parts used

• Aerial part

Dosage forms available

Usual dosages

Composition

Main components of the plant

• Flavonoids derived from myricetol , kaempferol and quercetol
• Major flavonoid : myricitroside , with isomyricitroside , isoquercitroside
• Myracetol-3-O-beta-D-glucuronide
• Tannins  : oenotheine B
• Beta-sitosterol , sterol esters

Main components of buds or young shoots

Main components of essential oil

Properties

Plant properties

• Antiphlogistic: Strongly inhibits experimental rat paw edema [1]
• Oenothein B stimulates the ability to attract neutrophils, modulates phagocytosis, but its isolated components are inactive ( pyrocatechol , gallic acid , pyrogallol , 3,4-dihydroxybenzoic acid ). Oenothein B is present in Epilobium angustifolium . [2]
• Tannins ( oenotheine B ) inhibit 5-alpha-reductase and aromatase activity [3]
• Inhibits the release of prostaglandins (active ingredient: myricetol-3-O-beta-D-glucuronide , 10 times more active than indomethacin.
• immune stimulant [4]
• prevention of prostate cancer [5]
• anti-aging properties. [6]

Bud properties

Properties of essential oil

Indications

Indications of the whole plant (phytotherapy)

• Benign prostatic hypertrophy and associated voiding disorders
• epididymite, orchitis, prostatitis

Indications of the bud (gemmotherapy)

Specific indications of essential oil (aromatherapy)

Known or suspected mode of action

• Myricetol -3-O-beta-D-glucuronide inhibits the release of prostaglandins
• Tannins inhibit 5-alpha-reductase and aromatase activity

Usual formulations

• Infusion of flowering aerial parts of small-flowered willowherb:
  • 6 grams for a cup of boiling water; infuse for a quarter of an hour. Drink in the evening.
• Hydroalcohol or mother tincture:
  • 50 drops morning and evening

Regulations

Possible side effects and precautions for use

Bibliographic references

1. Go↑ Hiermann A1, Reidlinger M, Juan H, Sametz W. Isolation of the antiphlogistic principle from Epilobium angustifolium. Planta Med. 1991 Aug;57(4):357-60.
2. Go↑ Igor A. Schepetkin, Liliya N. Kirpotina, Larissa Jakiw, Andrei I. Khlebnikov, Christie L. Blaskovich, Mark A. Jutila, Mark T. Quinn. Immunomodulatory Activity of Oenothein B Isolated from Epilobium angustifolium. The Journal of Immunology, 2009, vol. 183 no. 10, pp 6754-6766
3. Go↑ D. Lesuisse, J. Berjonneau, C. Ciot, P. Devaux, B. Doucet, J. F. Gourvest, B. Khemis, C. Lang, R. Legrand, M. Lowinski, P. Maquin, A. Parent, B. Schoot, G. Teutsch. Determination of Oenothein B as the Active 5-α-Reductase-Inhibiting Principle of the Folk Medicine Epilobium parviflorum. J. Nat. Prod., 1996, 59 (5), pp 490–492. PMID 8778238
4. Go↑ Ramstead AG1, Schepetkin IA, Quinn MT, Jutila MA. Oenothein B, a cyclic dimeric ellagitannin isolated from Epilobium angustifolium, enhances IFNγ production by lymphocytes. PLoS One. 2012;7(11):e50546.
5. Go↑ Stolarczyk M1, Naruszewicz M, Kiss AK. Extracts from Epilobium sp. herbs induce apoptosis in human hormone-dependent prostate cancer cells by activating the mitochondrial pathway. J Pharm Pharmacol. 2013 Jul;65(7):1044-54.
6. Go↑ Ruszová E1, Cheel J, Pávek S, Moravcová M, Hermannová M, Matějková I, Spilková J, Velebný V, Kubala L. Epilobium angustifolium extract demonstrates multiple effects on dermal fibroblasts in vitro and skin photo-protection in vivo. Gen Physiol Biophys. 2013 Sep; 32 (3): 347-59

• I. Slacanin, A. Marston, K. Hostettmann, N. Delabays, C. Darbellay. Isolation and determination of flavonol glycosides from epilobium species. Journal of Chromatography A, Volume 557, 20 September 1991, Pages 391-398 [1]

Store in a cool, dry place, away from light. Keep tightly closed, away from the reach of Children and pets.

Do not exceed the daily dose.

This product is not intended to prevent or cure any form of illness or disease.
 

If you are pregnant or nursing ; If you have a medical condition or are in the course of medical treatment ; If you are programmed for theater/operation in the near future, please consult your healthcare practitioner before using this product.

This product cannot replace a varied and balanced diet and a healthy lifestyle.

This product has not been evaluated by the SAHPRA for its quality, safety or intended use.

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