Lemon Balm Dried Organic (Melissa officinalis) - 60 g - Herbal Collection
Lemon balm (Melissa officinalis) is a perennial herb in the mint family native to the Mediterranean region.
It has been used for centuries for its medicinal properties and benefits.
The leaves of the plant have a lemony aroma and are rich in various bioactive compounds, including flavonoids, terpenoids, and phenolic acids.
Here are some of the key properties and benefits of lemon balm leaves:
- Anxiolytic and antidepressant effects: Lemon balm has been shown to help reduce anxiety and stress, and may have mild antidepressant effects. Its calming properties are attributed to the presence of compounds such as rosmarinic acid and other terpenoids, which interact with neurotransmitters in the brain.
- Cognitive enhancement: Lemon balm has been found to improve cognitive function and memory, possibly by inhibiting the enzyme acetylcholinesterase, which breaks down the neurotransmitter acetylcholine.
- Sleep improvement: Lemon balm is often used as a natural remedy for insomnia and sleep disorders due to its mild sedative properties. It may help relax the nervous system, making it easier to fall asleep and stay asleep.
- Antioxidant and anti-inflammatory properties: Lemon balm is rich in antioxidants, which can help protect the body from damage caused by free radicals. Additionally, its anti-inflammatory properties may help reduce inflammation and alleviate symptoms of various inflammatory conditions.
- Antiviral and antimicrobial properties: Lemon balm has demonstrated antiviral properties against viruses such as herpes simplex, and its essential oil has shown antimicrobial activity against a range of bacteria and fungi. This makes it a potential natural remedy for minor infections and skin conditions.
- Digestive health: Lemon balm has been traditionally used to alleviate digestive discomfort, such as bloating, gas, and indigestion. It may help relax the muscles of the gastrointestinal tract and has antispasmodic properties that can ease cramps and stomach pain.
- Cardiovascular benefits: Some studies suggest that lemon balm may have a positive effect on heart health by reducing blood pressure, improving blood lipid profiles, and reducing the risk of heart disease.
- Support for the immune system: Lemon balm may help boost the immune system by stimulating the production of immune cells and enhancing their function.
It is important to note that while lemon balm has many potential benefits, more research is needed to fully understand its effects and confirm its efficacy. As with any herbal supplement, it's crucial to consult with a healthcare professional before using lemon balm, especially if you are pregnant, breastfeeding, or taking medication.
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Melissa, lemon balm (English)
International Latin denomination
Description and habitat
- Herbaceous plant from 30 to 80 cm sometimes spontaneous in cool and shady places, cultivated throughout Europe
- Oval, dark green, embossed and serrated leaves, with a very pleasant lemony smell
- Flowers in axillary cyme with a white corolla sometimes spotted with pink
History and tradition
- Lemon balm has been used since Hippocrates (4th century BC) and Theophrastus (3rd century BC), then by Paracelsus (15th century AD)
- Its name would come from the Latin "melissophyllon", itself coming from the Greek "phyllon" (leaf) and "melissa" (bee), because it is a very honey-producing plant 
- It was used in sorrows (to drive away dark thoughts) and as a cordial (drink intended to stimulate the functioning of the heart)
- We find this use in the liqueurs of the monks of the Chartreuse, the Carmelites, and the Benedictines 
- Dried leaf and leafy stem
- Essential oil distilled from the leaves
Dosage forms available
- Sedative at low dose from 12.5 to 25 mg/kg in mice
- Reduces stress at a dose of 600 mg of extract per day
Main components of the plant
- Essential oil (0.05 - 0.3%) with 50% citrals (mixture of geranial and neral ) and citronellal (lemon aroma)
- Monoterpene glycosides
- 4% rosmarinic acid (called "tannin of the Labiatae" or Lamiaceae ), chlorogenic acid and caffeic acid ,
- Triterpenes ( ursolic acid , oleanolic acid and hydroxyoleanolic acid )
- Uronic mucilages
- Flavonoids (derived from luteolin , quercetin )
Main components of buds or young shoots
Main components of essential oil
- Aldehydes : majority citrals (up to 90%) = geranial ( citral a 20-35%) & neral ( citral b 15-25%), citronellal 3-5%
- Ketones : isomenthone , menthone , 6-methyl-5-hepten-2-one
- Monoterpenes and sesquiterpenes : beta-caryophyllene 15-20%, germacrene-D 5-10%
- Monoterpene alcohols : linalool , geraniol
- Sedative, reduces stress at a dose of 600 mg of extract per day 
- Anxiolytic  , anxiolytic effect accentuated in combination with valerian 
- Lemon balm acts at the level of GABA-ergic receptors, inhibits the activity of gamma-aminobutyric acid transaminase (GABA-transaminase), increases the level of GABA in the brain by inhibiting its catabolism  ,  ( rosmarinic acid , triterpenoids : ursolic acid , oleanolic acid )
- The aqueous extract of Melissa officinalis showed the strongest inhibition of GABA transaminase activity in various plant extracts tested 
- GABA-A receptors are the target of anxiolytics of the benzodiazepine family which potentiate its inhibitory effect on the central nervous system. Gamma-amino butyric acid ( GABA ) is the major inhibitory neurotransmitter in the central nervous system
- Melissa officinalis extract inhibits the activity of the enzyme acetylcholinesterase  , which increases the influence of acetylcholine (peripheral and potential parasympathicotonic activity in Alzheimer's disease)
- Anticonvulsant 
- Lemon balm leaves exert a spasmolytic and digestive stimulating action, coupled with a sedative and tranquilizing effect comparable to that obtained with benzodiazepines
- Anti-ulcer 
- Antiviral (antiherpetic)  ,  , especially the aqueous extract, applied topically  , and bactericidal ( rosmarinic acid )
- Anti-oxidant  , the most effective components being monoterpene aldehydes ( neral / geranial , citronellal ) and ketones ( isomenthone , menthone ), monoterpenes and sesquiterpenes ( beta-caryophyllene )
- Neuroprotective 
- Lemon balm improves symptoms of mild Alzheimer's disease and decreases restlessness  ,  ,  , 
- Melissa officinalis promotes sleep in cases of onset insomnia, can be used in benzodiazepine withdrawal syndrome  and opioid withdrawal in a dose-dependent manner 
- Presumably antidepressant, improves mood and cognitive performance  , modulation of muscarinic and nicotinic receptors  , improves memory 
- Analgesic 
- May interfere with thyroid function, decrease TSH binding to its receptor  ,  , 
Properties of essential oil
- Spasmolytic with an effect identical to papaverine by inhibiting the response induced by KCl (80 mM), ACh (320 nM) and 5-HT (1.28 μM), in a dose-dependent manner 
- Antioxidant and free radical scavenger 
- Antiviral against herpes virus I and II  ,  , and influenza A H9N2 
- Antibacterial ( Shigella sp : Mimica-Dukic)
- Antifungal ( Trichophyton sp : Mimica-Dukic)
- Anticancer in many human and mouse cell models  , 
- Anti-tumor and antioxidant 
- Calming  , reduction of agitation  even in cases of dementia 
Indications of the whole plant (phytotherapy)
- Functional gastrointestinal disorders
- Nervousness, insomnia, anxiety, demonstrative clinical studies 
- Dysmenorrhea and premenstrual syndrome 
- Cardiac problems of psycho-vegetative origin
- Biliary pain ( rosmarinic acid , Lamiaceae tannin ) and essential oil )
- Hypertonic dyskinesia
- Nervous breakdown
- Hyperthyroidism, the components with antithyrotropic activity of extracts of Lycopus virginicus , Lycopus europaeus , Melissa officinalis , Lithospermum officinale can interact with immunoglobulins G specific for Graves' disease and inhibit their ability to bind to the TSH receptor 
Indications of the bud (gemmotherapy)
Specific indications of essential oil (aromatherapy)
- Hysteria, nervous breakdown
- Irritable Bowel Syndrome 
- Labial and genital herpes in local applications in 1% cream 
Known or suspected mode of action
- The anxiolytic properties are probably due to a potentiation of GABA , by inhibition of the enzyme GABA transaminase (GABA-T), target of therapies for anxiety, epilepsy and other neurological disorders ( rosmarinic acid , triterpenoids : ursolic acid , oleanolic acid ) 
- Rosmarinic acid is antiviral
- Citrals and citronellal would be anti-cancer  ,  ,  and sedative
- The free radical scavenging effect is related to the presence of neral , geranial , citronellal , isomenthone , menthone ( geranial or citral a ( trans form ) neral or citral b ( cis form ) are stereoisomers)
- Cinnamic acid derivatives inhibit the binding of TSH to human thyroid membranes: caffeic acid , rosmarinic acid , chlorogenic acid , ellagic acid 
- Lemon Balm EPS Melissa officinalis : 5 to 10 ml per day (i.e. one to two teaspoons).
- TM Melissa officinalis : 50 drops in the evening before meals and 100 drops at bedtime.
- Élusanes® ( dry extract ) of lemon balm: 1 capsule morning and evening
- EO of pure lemon balm in local applications on herpes pimples, several times a day
- French Pharmacopoeia list A (leaf, flowering top)
Possible side effects and precautions for use
- Perfectly tolerated up to 500 mg of rosmarinic acid 
- A case of addiction has reportedly been reported 
- Beware of interactions with thyroid function 
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Store in a cool, dry place, away from light. Keep tightly closed, away from the reach of Children and pets.
Do not exceed the daily dose.
This product is not intended to prevent or cure any form of illness or disease.
If you are pregnant or nursing ; If you have a medical condition or are in the course of medical treatment ; If you are programmed for theater/operation in the near future, please consult your healthcare practitioner before using this product.
This product cannot replace a varied and balanced diet and a healthy lifestyle.
This product has not been evaluated by the SAHPRA for its quality, safety or intended use.